N-Carbethoxyphthalimide
Synonym(s):N-Ethoxycarbonylphthalimide;Ethyl 1,3-dioxo-2-isoindolinecarboxylate;Ethyl phthalimide-N-carboxylate
- CAS NO.：22509-74-6
- Empirical Formula: C11H9NO4
- Molecular Weight: 219.19
- MDL number: MFCD00005893
- EINECS: 245-048-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:56
What is N-Carbethoxyphthalimide?
Chemical properties
White crystalline powder
The Uses of N-Carbethoxyphthalimide
N-Carbethoxyphthalimide is used in the synthetic preparation of a novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Purification Methods
Crystallise the imide from toluene/pet ether (or *benzene/pet ether). It is partly soluble in Et2O, *benzene and CHCl3. [Heller & Jacobsohn Chem Ber 54 1112 1921, Beilstein 21/10 V 428.]
Properties of N-Carbethoxyphthalimide
| Melting point: | 90-92 °C(lit.) |
| Boiling point: | 360°C (rough estimate) |
| Density | 1.3219 (rough estimate) |
| vapor pressure | 0.003-0.006Pa at 20-25℃ |
| refractive index | 1.4950 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | -3.02±0.20(Predicted) |
| form | Crystalline Powder |
| color | White |
| Water Solubility | insoluble |
| BRN | 196340 |
| CAS DataBase Reference | 22509-74-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 2H-isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester(22509-74-6) |
| EPA Substance Registry System | 2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester (22509-74-6) |
Safety information for N-Carbethoxyphthalimide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for N-Carbethoxyphthalimide
| InChIKey | VRHAQNTWKSVEEC-UHFFFAOYSA-N |
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
You may like
-
22509-74-6 N-Carbethoxyphthalimide 99%View Details
22509-74-6 -
N-Carbethoxyphthalimide 98% CAS 22509-74-6View Details
22509-74-6 -
N-Ethoxycarbonylphthalimide [for Peptide Synthesis] CAS 22509-74-6View Details
22509-74-6 -
N-Carbethoxyphthalimide CAS 22509-74-6View Details
22509-74-6 -
674783-97-2 98+View Details
674783-97-2 -
H-D-TRP(FOR)-OH HCL 98+View Details
367453-01-8 -
1428243-26-8 98+View Details
1428243-26-8 -
1-aminocyclopentane carbonitrile, HCl 98+View Details
16195-83-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.