N-Boc-piperidine-2-methanol
Synonym(s):N-Boc-2-(hydroxymethyl)piperidine;2-Hydroxymethylpiperidine-1-carboxylic acid tert-butyl ester
- CAS NO.：157634-00-9
- Empirical Formula: C11H21NO3
- Molecular Weight: 215.29
- MDL number: MFCD04114966
- EINECS: 627-195-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:01
What is N-Boc-piperidine-2-methanol?
Chemical properties
Solid
The Uses of N-Boc-piperidine-2-methanol
Reactant for:
- Julia coupling for synthesis of corydendramine A
- Cyclization-functionalization of nitrogen-containing dienes
Reactant for synthesis of:
- Heterocyclic compounds
- Anthranilamide inhibitors of factor Xa
- Human GnRH receptor antagonists
- Sphingosine-1-phosphate receptor agonists
Properties of N-Boc-piperidine-2-methanol
| Melting point: | 74-78 °C |
| Boiling point: | 308.0±15.0 °C(Predicted) |
| Density | 1.059±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| form | Crystalline Powder |
| pka | 15.08±0.10(Predicted) |
| color | White |
| CAS DataBase Reference | 157634-00-9(CAS DataBase Reference) |
Safety information for N-Boc-piperidine-2-methanol
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for N-Boc-piperidine-2-methanol
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