N-Acetyl Retigabine

CAS NO.：229970-68-7
Empirical Formula: C15H16FN3O
Molecular Weight: 273.31
MDL number: MFCD19705069
EINECS: 806-047-0
Update Date: 2026-05-27 23:24:43

What is N-Acetyl Retigabine?

The Uses of N-Acetyl Retigabine

N-Acetyl N-Descarboxyethyl Retigabine, is a metabolite of Retigabine (R189050), a new experimental anticonvulsant drug. Anxiolytic.

General Description

A Certified Spiking Solution^? suitable for use in retigabine testing methods by LC/MS or GC/MS for applications in clinical toxicology, medication monitoring, urine drug testing, pharmaceutical research, or forensic analysis. N-Acetylretigabine is the primary urinary metabolite of retigabine, a new antiepileptic drug developed for treatment of partial seizures. Also known as ezogabine, the drug is marketed under the trade names Potiga^? in the US and Trobalt in the EU.

Properties of N-Acetyl Retigabine

Melting point:	153-155°C
Boiling point:	509.6±50.0 °C(Predicted)
Density	1.306±0.06 g/cm3(Predicted)
Flash point:	2℃
storage temp.	-20°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	14.38±0.70(Predicted)
color	Pale Grey to Brown

Safety information for N-Acetyl Retigabine

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.