N-Acetyl Retigabine
- CAS NO.：229970-68-7
- Empirical Formula: C15H16FN3O
- Molecular Weight: 273.31
- MDL number: MFCD19705069
- EINECS: 806-047-0
- Update Date: 2026-01-13 11:13:43
What is N-Acetyl Retigabine?
The Uses of N-Acetyl Retigabine
N-Acetyl N-Descarboxyethyl Retigabine, is a metabolite of Retigabine (R189050), a new experimental anticonvulsant drug. Anxiolytic.
General Description
A Certified Spiking Solution? suitable for use in retigabine testing methods by LC/MS or GC/MS for applications in clinical toxicology, medication monitoring, urine drug testing, pharmaceutical research, or forensic analysis. N-Acetylretigabine is the primary urinary metabolite of retigabine, a new antiepileptic drug developed for treatment of partial seizures. Also known as ezogabine, the drug is marketed under the trade names Potiga? in the US and Trobalt in the EU.
Properties of N-Acetyl Retigabine
| Melting point: | 153-155°C |
| Boiling point: | 509.6±50.0 °C(Predicted) |
| Density | 1.306±0.06 g/cm3(Predicted) |
| Flash point: | 2℃ |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 14.38±0.70(Predicted) |
| color | Pale Grey to Brown |
Safety information for N-Acetyl Retigabine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Acetyl Retigabine
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