N-Acetyl-L-leucine
- CAS NO.：1188-21-2
- Empirical Formula: C8H15NO3
- Molecular Weight: 173.21
- MDL number: MFCD00065131
- EINECS: 214-706-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 17:10:26
What is N-Acetyl-L-leucine?
Chemical properties
White crystalline powder
The Uses of N-Acetyl-L-leucine
N-Acetyl-L-(-)-leucine is used in the preparation of small molecule inhibitors of anti-apoptotic Bcl-2 family proteins. Also used in the preparation of amphiphilic copolymers involving hydrophobic amino acid and oligopeptide side chains for optical tumor imaging in vivo.
What are the applications of Application
N-Acetyl-L-leucine is a derivative of L-leucine carrying an N-acylated aliphatic chain
Definition
ChEBI: The N-acetyl derivative of L-leucine.
Properties of N-Acetyl-L-leucine
| Melting point: | 187-190 °C(lit.) |
| Boiling point: | 303.86°C (rough estimate) |
| alpha | -24.5 º (c=4, MeOH) |
| Density | 1.1599 (rough estimate) |
| refractive index | -22 ° (C=5, EtOH) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Ethanol (Slightly), Water (Slightly, Heated) |
| form | Crystalline Powder |
| pka | 3.67±0.10(Predicted) |
| color | White |
| optical activity | [α]25/D 23±3°, c = 2 in ethanol |
| Water Solubility | 0.81 g/100 mL (20 ºC) |
| BRN | 1724849 |
| CAS DataBase Reference | 1188-21-2(CAS DataBase Reference) |
| NIST Chemistry Reference | L-leucine, n-acetyl-(1188-21-2) |
| EPA Substance Registry System | L-Leucine, N-acetyl- (1188-21-2) |
Safety information for N-Acetyl-L-leucine
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for N-Acetyl-L-leucine
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