MURISTERONE A
- CAS NO.：38778-30-2
- Empirical Formula: C27H44O8
- Molecular Weight: 496.63
- MDL number: MFCD00056450
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-20 16:56:14
What is MURISTERONE A?
Description
Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.
The Uses of MURISTERONE A
Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.
What are the applications of Application
Muristerone A is a potent inducer of ecdysone-inducible genes
Biological Activity
Ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.
Storage
+4°C
Properties of MURISTERONE A
| Boiling point: | 707.2±60.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Soluble in DMSO |
| form | solid |
| pka | 11.78±0.70(Predicted) |
| color | white |
Safety information for MURISTERONE A
Computed Descriptors for MURISTERONE A
MURISTERONE A manufacturer
GK Chemicals
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