Muramyl Dipeptide
Synonym(s):RDP;MDP;Muramyl dipeptide;Adjuvant Peptide;Dehydropeptidase-I
- CAS NO.：53678-77-6
- Empirical Formula: C19H32N4O11
- Molecular Weight: 492.48
- MDL number: MFCD00077638
- EINECS: 258-696-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 15:00:32
What is Muramyl Dipeptide?
The Uses of Muramyl Dipeptide
Immunological adjuvant.
The Uses of Muramyl Dipeptide
N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate has been used in staphylococcal cell wall preparation to induce the release of TNF from human monocytes.
Biochem/physiol Actions
Muramyl peptides are monomeric components that make up the bacterial cell wall peptidoglycan. It is generally produced by mammalian macrophages, as an immune response in the breakdown of bacterial cell wall. MDP promotes the production of interleukin-1 and tumor necrosis factor (TNF), which increase slow-wave sleep.
Properties of Muramyl Dipeptide
| Boiling point: | 1071.8±65.0 °C(Predicted) |
| alpha | D25 +44° (acetic acid) |
| Density | 1.390±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: 10 mg/mL, clear, colorless |
| pka | 4.44±0.10(Predicted) |
| form | buffered aqueous solution |
| color | White to off-white |
| Merck | 13,6329 |
| BRN | 4220745 |
| CAS DataBase Reference | 53678-77-6(CAS DataBase Reference) |
Safety information for Muramyl Dipeptide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Muramyl Dipeptide
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