MILBEMECTIN A4
- CAS NO.：51596-11-3
- Empirical Formula: C32H46O7
- Molecular Weight: 542.7
- MDL number: MFCD04972570
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 15:05:59
What is MILBEMECTIN A4?
Description
Milbemycin A4 is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin 4 is used as a nematocide and insecticide.
The Uses of MILBEMECTIN A4
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.
The Uses of MILBEMECTIN A4
Acaricide.
The Uses of MILBEMECTIN A4
Milbemycin A4 is a macrolide compound that is a member of a complex family of macrocyclic lactones that contain structural group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. Antibacterial and insecticide (1,2). It potentiates glutamate and GABA-gated chloride-channel opening. Used in the synthesis of Milbemycin A17 (3).
What are the applications of Application
Milbemycin A4 is an antibiotic with acaricidal activity
Definition
ChEBI: Milbemycin A4 is a milbemycin.
Properties of MILBEMECTIN A4
| Melting point: | 212-215° |
| Boiling point: | 732.9±60.0 °C(Predicted) |
| alpha | D20 +106° (c = 0.25 in acetone) |
| Density | 1.20±0.1 g/cm3(Predicted) |
| storage temp. | 0-6°C |
| solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble |
| form | A solid |
| pka | 12.46±0.70(Predicted) |
| color | White to off-white |
| EPA Substance Registry System | Milbemycin A4 (51596-11-3) |
Safety information for MILBEMECTIN A4
Computed Descriptors for MILBEMECTIN A4
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