methylnaltrexone
- CAS NO.：83387-25-1
- Empirical Formula: C21H26NO4+
- Molecular Weight: 356.43544
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 17:10:26
What is methylnaltrexone?
Definition
ChEBI: Methylnaltrexone is a member of phenanthrenes.
General Description
Methylnaltrexone (Relistor) is the methylated, quaternaryform of naltrexone . The permanently chargednitrogen prevents the drug from crossing the blood-brainbarrier. Thus, it only acts as an antagonist at peripheralopioid receptors. Relistor was approved in April 2008 totreat opioid-induced constipation in patients receiving palliativecare. It is administered as a SC injection once everyother day.
Safety information for methylnaltrexone
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