Methyl-piperidino-pyrazole hydrate
Synonym(s):1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride hydrate;Methyl-piperidino-pyrazole hydrate
- CAS NO.：911295-24-4
- Empirical Formula: C29H32ClN3O3
- Molecular Weight: 506.04
- MDL number: MFCD06411603
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-20 17:00:22
What is Methyl-piperidino-pyrazole hydrate?
The Uses of Methyl-piperidino-pyrazole hydrate
MPP Dihydrochloride is a pharmacological estrogen receptor antagonist. It cannot block EE2 induced luciferase activity with any isoform of zebrafish estrogen receptor.
The Uses of Methyl-piperidino-pyrazole hydrate
MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:
- in human breast cancer MCF-7 cells
- to pre-treat endometrial ex vivo organ cultures (EVOCs)
- to treat pituitary glands to monitor luteinizing hormone secretion
General Description
Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol.
Biochem/physiol Actions
MPP dihydrochloride is a specific estrogen receptor α antagonist.
Storage
+4°C (desiccate)
Properties of Methyl-piperidino-pyrazole hydrate
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble ≥20mg/mL |
| form | white powder |
| color | White to off-white |
Safety information for Methyl-piperidino-pyrazole hydrate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Methyl-piperidino-pyrazole hydrate
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile BudesonideYou may like
-
MPP dihydrochloride hydrate CAS 911295-24-4View Details
911295-24-4 -
1589503?95?6 2-((2,6-Difluorobenzyl)(ethoxycarbonyl)amino)-4-((dimethylamino)methyl)-5-(4-nitrophenyl)thiophene-3-carboxylic acid 99%View Details
1589503?95?6 -
2-Chlorophenyl diphenyl chloromethane 99%View Details
42074-68-0 -
6-(chloromethyl)pteridine-2,4-diamine monohydrochloride 82778?08?3 99%View Details
82778?08?3 -
1,3-Dibromo-5-fluorobenzene 99%View Details
1435-51-2 -
729559-09-5 [N(E)]-N-Ethylidene-2-methyl-2-propanesulfinamide 99%View Details
729559-09-5 -
4-Isopropyl Thiophenol 4946-14-9 99%View Details
4946-14-9 -
2709271-25-8 99%View Details
2709271-25-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.