Methyl-piperidino-pyrazole hydrate
Synonym(s):1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride hydrate;Methyl-piperidino-pyrazole hydrate
- CAS NO.：911295-24-4
- Empirical Formula: C29H32ClN3O3
- Molecular Weight: 506.04
- MDL number: MFCD06411603
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is Methyl-piperidino-pyrazole hydrate?
The Uses of Methyl-piperidino-pyrazole hydrate
MPP Dihydrochloride is a pharmacological estrogen receptor antagonist. It cannot block EE2 induced luciferase activity with any isoform of zebrafish estrogen receptor.
The Uses of Methyl-piperidino-pyrazole hydrate
MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:
- in human breast cancer MCF-7 cells
- to pre-treat endometrial ex vivo organ cultures (EVOCs)
- to treat pituitary glands to monitor luteinizing hormone secretion
General Description
Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol.
Biochem/physiol Actions
MPP dihydrochloride is a specific estrogen receptor α antagonist.
Storage
+4°C (desiccate)
Properties of Methyl-piperidino-pyrazole hydrate
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble ≥20mg/mL |
| form | white powder |
| color | White to off-white |
Safety information for Methyl-piperidino-pyrazole hydrate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Methyl-piperidino-pyrazole hydrate
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