Methyl indolyl-3-glyoxylate
Synonym(s):Methyl 2-(indol-3-yl)-2-oxoacetate
- CAS NO.：18372-22-0
- Empirical Formula: C11H9NO3
- Molecular Weight: 203.19
- MDL number: MFCD00047173
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:21
What is Methyl indolyl-3-glyoxylate?
Chemical properties
Pale Yellow Fine Powder
The Uses of Methyl indolyl-3-glyoxylate
Methyl Indolyl-3-glyoxylate (cas# 18372-22-0) is a compound useful in organic synthesis.
The Uses of Methyl indolyl-3-glyoxylate
Reactant for preparation of sotrastaurin analogs as protein kinase inhibitors 1 Reactant for synthesis of GSK-3 inhibitors 2 Reactant for Diels-Alder cycloaddition 3 Reactant for preparation of a Janus kinase 3 inhibitor 4 Reactant for synthesis of cephalandole alkaloids 5 Reactant for stereoselective preparation of COX-2 inhibitor as anticancer agent 6 Reactant for synthesis of cycloalkene indole carbazole alkaloids via ring-closing metathesis.
Properties of Methyl indolyl-3-glyoxylate
| Melting point: | 227-230 °C (lit.) |
| Boiling point: | 383.2±15.0 °C(Predicted) |
| Density | 1.324±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetone, Methanol |
| form | Solid |
| pka | 14.54±0.30(Predicted) |
| color | Pale Yellow Fine |
| Stability: | Temperature Sensitive |
| CAS DataBase Reference | 18372-22-0(CAS DataBase Reference) |
Safety information for Methyl indolyl-3-glyoxylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Methyl indolyl-3-glyoxylate
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