Methoxyphenamine
- CAS NO.：93-30-1
- Empirical Formula: C11H17NO
- Molecular Weight: 179.25878
- MDL number: MFCD00864153
- EINECS: 202-237-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-21 14:17:16
What is Methoxyphenamine?
Chemical properties
Oily liquid. Boiling point 97-99 ℃ (0.267kPa). Its hydrochloride is a white crystalline powder with a melting point of 129-131 °C. Soluble in water, ethanol, chloroform, slightly soluble in benzene and ether. Odorless, bitter taste. The pH of a 5% aqueous solution is 5.3-5.7.
The Uses of Methoxyphenamine
Methoxyphenamine is an adrenaline-mimetic drug with significant bronchodilation and smooth muscle relaxation effects. It also has a mild antihistamine effect, a sedative effect and suppresses the cough center. It is suitable for treating bronchial asthma, especially for patients who cannot tolerate ephedrine.
Definition
ChEBI: Methoxyphenamine is an amphetamine methylated on nitrogen and with the phenyl ring methoxylated at C-2. A beta-adrenergic receptor agonist, it is used as a bronchodilator. It has a role as a beta-adrenergic agonist and a bronchodilator agent.
Synthesis
Methoxyphenamine is obtained by methylation and reduction of o-methoxypropiophenone.
Metabolism
Not Available
Properties of Methoxyphenamine
| Melting point: | 271℃ |
| Boiling point: | 252℃ |
| Density | 0.951 |
| Flash point: | 103℃ |
| pka | 10.36±0.10(Predicted) |
Safety information for Methoxyphenamine
Computed Descriptors for Methoxyphenamine
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