Mestanolone

Synonym(s):Mestanolone;Methylandrostanolone;Mestaline;17α-Methyldihydrotestosterone;17β-Hydroxy-17α-methyl-5α-androstan-3-one

CAS NO.：521-11-9
Empirical Formula: C20H32O2
Molecular Weight: 304.47
MDL number: MFCD00021158
EINECS: 208-302-6
SAFETY DATA SHEET (SDS)
Update Date: 2025-04-16 17:28:31

What is Mestanolone?

Description

Mestanolone is an orally active anabolic-androgenic steroid and the 17α-methylated derivative of dihydrotestosterone (DHT), which is an endogenous androgen sex steroid and hormone. It is capable of increasing testosterone benefit, suppressing estrogen effect, leaning muscle tissue, increasing strength as well as improving drive and focus. It is mainly used for the treatment of male hypogonadism and decreased sperm infertility.

Chemical properties

White Solid

The Uses of Mestanolone

Anabolic steroid. Controlled substance.

Definition

ChEBI: Mestanolone is a 3-oxo-5alpha-steroid.

Purification Methods

Dissolve mestanolone in Et2O, wash it with N NaOH, H2O, dry it (Na2SO4), evaporate and recrystallise it from EtOAc. The semicarbazone has m 235-236o (from EtOH). [Ruzicka et al. Helv Chim Acta 18 1487 1935.]

References

https://en.wikipedia.org/wiki/Mestanolone
https://en.wikipedia.org/wiki/Dihydrotestosterone#Medical_use
http://www.biopharmchem.com/raw-hormone-ermalone-oral-steroid-mestanolone-p01138p1.html

Properties of Mestanolone

Melting point:	191 °C
Boiling point:	385.28°C (rough estimate)
Density	1.0279 (rough estimate)
refractive index	1.4824 (estimate)
storage temp.	Controlled Substance, -20°C Freezer
solubility	Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
pka	15.15±0.60(Predicted)
form	neat
Merck	5915
InChI	InChI=1/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h13,15-17,22H,4-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/s3
CAS DataBase Reference	521-11-9(CAS DataBase Reference)
NIST Chemistry Reference	Mestanolone(521-11-9)

Safety information for Mestanolone

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H351:Carcinogenicity H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention.