Mestanolone
Synonym(s):Mestanolone;Methylandrostanolone;Mestaline;17α-Methyldihydrotestosterone;17β-Hydroxy-17α-methyl-5α-androstan-3-one
- CAS NO.：521-11-9
- Empirical Formula: C20H32O2
- Molecular Weight: 304.47
- MDL number: MFCD00021158
- EINECS: 208-302-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-16 17:28:31
What is Mestanolone?
Description
Mestanolone is an orally active anabolic-androgenic steroid and the 17α-methylated derivative of dihydrotestosterone (DHT), which is an endogenous androgen sex steroid and hormone. It is capable of increasing testosterone benefit, suppressing estrogen effect, leaning muscle tissue, increasing strength as well as improving drive and focus. It is mainly used for the treatment of male hypogonadism and decreased sperm infertility.
Chemical properties
White Solid
The Uses of Mestanolone
Anabolic steroid. Controlled substance.
Definition
ChEBI: Mestanolone is a 3-oxo-5alpha-steroid.
Purification Methods
Dissolve mestanolone in Et2O, wash it with N NaOH, H2O, dry it (Na2SO4), evaporate and recrystallise it from EtOAc. The semicarbazone has m 235-236o (from EtOH). [Ruzicka et al. Helv Chim Acta 18 1487 1935.]
References
https://en.wikipedia.org/wiki/Mestanolone
https://en.wikipedia.org/wiki/Dihydrotestosterone#Medical_use
http://www.biopharmchem.com/raw-hormone-ermalone-oral-steroid-mestanolone-p01138p1.html
Properties of Mestanolone
| Melting point: | 191 °C |
| Boiling point: | 385.28°C (rough estimate) |
| Density | 1.0279 (rough estimate) |
| refractive index | 1.4824 (estimate) |
| storage temp. | Controlled Substance, -20°C Freezer |
| solubility | Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml |
| pka | 15.15±0.60(Predicted) |
| form | neat |
| Merck | 5915 |
| InChI | InChI=1/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h13,15-17,22H,4-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/s3 |
| CAS DataBase Reference | 521-11-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Mestanolone(521-11-9) |
Safety information for Mestanolone
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H351:Carcinogenicity H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for Mestanolone
| InChIKey | WYZDXEKUWRCKOB-YDSAWKJFSA-N |
| SMILES | C[C@]12CCC(=O)C[C@]1([H])CC[C@@]1([H])[C@]3([H])CC[C@@](O)(C)[C@@]3(C)CC[C@]21[H] |&1:1,7,11,13,17,20,24,r| |
Mestanolone manufacturer
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