Menthoxypropanediol
- CAS NO.：87061-04-9
- Empirical Formula: C13H26O3
- Molecular Weight: 230.34
- MDL number: MFCD06410978
- EINECS: 289-296-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-03 14:17:14
What is Menthoxypropanediol?
Chemical properties
3-[(l)-Menthoxy]propane-1,2-diol is a liquid that gives a
physiological cooling sensation on the skin and mucosa. It is used to create coolness
and freshness to cosmetic and oral care preparations.
The synthesis of menthoxypropanediol starts with menthol. Subsequent etherification
with an allyl halide and dihydroxylation yields the diol.
The Uses of Menthoxypropanediol
Menthoxypropanediol is used to mask odor and leave the skin feeling refreshed, it is a synthetic menthol derivative.
The Uses of Menthoxypropanediol
Menthoxypropane-1,2-diol, is a Cyclohexane derivative are disclosed in a variety of tech. products, household products, or in cosmetic and pharmaceutical compounds.?The substances are well tolerated and characterized by their good biodegradability.
Definition
ChEBI: 3-[[5-Methyl-2-(1-methylethyl)cyclohexyl]oxy]-1,2-propanediol is a p-menthane monoterpenoid.
Flammability and Explosibility
Not classified
Trade name
Coolact® 10 (Takasago).
Properties of Menthoxypropanediol
| Boiling point: | 362.8±22.0 °C(Predicted) |
| Density | 1.00 |
| vapor pressure | 78Pa at 20℃ |
| refractive index | 1.474-1.480 |
| FEMA | 3784 | 3-L-MENTHOXYPROPANE-1,2-DIOL |
| Flash point: | 177 °C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Thick Oil |
| pka | 13.65±0.20(Predicted) |
| color | Colourless |
| Odor | at 100.00 %. very mild minty phenolic fruity jammy dried fruit berry |
| Water Solubility | 2.27g/L at 20℃ |
| JECFA Number | 1408 |
| EPA Substance Registry System | 1,2-Propanediol, 3-[[5-methyl-2-(1-methylethyl)cyclohexyl]oxy]- (87061-04-9) |
Safety information for Menthoxypropanediol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Menthoxypropanediol
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