Menthoxypropanediol

CAS NO.：87061-04-9
Empirical Formula: C13H26O3
Molecular Weight: 230.34
MDL number: MFCD06410978
EINECS: 289-296-2
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 05:12:52

What is Menthoxypropanediol?

Chemical properties

3-[(l)-Menthoxy]propane-1,2-diol is a liquid that gives a physiological cooling sensation on the skin and mucosa. It is used to create coolness and freshness to cosmetic and oral care preparations.
The synthesis of menthoxypropanediol starts with menthol. Subsequent etherification with an allyl halide and dihydroxylation yields the diol.

The Uses of Menthoxypropanediol

Menthoxypropanediol is used to mask odor and leave the skin feeling refreshed, it is a synthetic menthol derivative.

The Uses of Menthoxypropanediol

Menthoxypropane-1,2-diol, is a Cyclohexane derivative are disclosed in a variety of tech. products, household products, or in cosmetic and pharmaceutical compounds.?The substances are well tolerated and characterized by their good biodegradability.

Definition

ChEBI: 3-[[5-Methyl-2-(1-methylethyl)cyclohexyl]oxy]-1,2-propanediol is a p-menthane monoterpenoid.

Flammability and Explosibility

Not classified

Trade name

Coolact® 10 (Takasago).

Properties of Menthoxypropanediol

Boiling point:	362.8±22.0 °C(Predicted)
Density	1.00
vapor pressure	78Pa at 20℃
refractive index	1.474-1.480
FEMA	3784 \| 3-L-MENTHOXYPROPANE-1,2-DIOL
Flash point:	177 °C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Thick Oil
pka	13.65±0.20(Predicted)
color	Colourless
Odor	at 100.00 %. very mild minty phenolic fruity jammy dried fruit berry
Water Solubility	2.27g/L at 20℃
JECFA Number	1408
EPA Substance Registry System	1,2-Propanediol, 3-[[5-methyl-2-(1-methylethyl)cyclohexyl]oxy]- (87061-04-9)

Safety information for Menthoxypropanediol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.