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HomeProduct name listMELOXICAM SODIUM SALT HYDRATE

MELOXICAM SODIUM SALT HYDRATE

Synonym(s):4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate;Metacam sodium salt hydrate;Mobec sodium salt hydrate;UH-AC 62XX sodium salt hydrate

MELOXICAM SODIUM SALT HYDRATE Structural

What is MELOXICAM SODIUM SALT HYDRATE?

The Uses of MELOXICAM SODIUM SALT HYDRATE

Meloxicam sodium salt hydrate has been used:

  • as a cyclooxygenase-2 (COX-2) inhibitor in solid Ehrlich tumor
  • as an alternative to diclofenac nonsteroidal anti-inflammatory drugs (NSAID) to treat vultures
  • as a reference standard in liquid chromatography electrospray ionisation mass spectrometry (LC-ESI/MS)
  • to test its effect on prostaglandin (PGE2) production in lipopolysaccharide (LPS)-induced COX-2 protein expression in RAW246.7 cells

What are the applications of Application

Meloxicam sodium salt is a Cox-2 inhibitor

Biochem/physiol Actions

Meloxicam, a member of the oxicam family, is a non-steroidal anti-inflammatory drug (NSAID). It is synthesized from piroxicam with aryl and the pyridyl ring substitution. Meloxicam is a cyclooxygenase-2 (COX-2) inhibitor, it may be useful in treating inflammation and pain. Meloxicam has been shown to stop thymulin-induced increas in concentration of cytokines and Nerve growth factor?(NGF) in the liver of rats. Meloxicam also suppresses tumor growth and may be capable of antagonizing cachexia?in vitro. It promotes apoptosis in hepatocellular carcinoma.

Properties of MELOXICAM SODIUM SALT HYDRATE

storage temp.  room temp
solubility  DMSO: soluble5mg/mL, clear
color  light yellow to dark yellow

Safety information for MELOXICAM SODIUM SALT HYDRATE

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for MELOXICAM SODIUM SALT HYDRATE

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