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HomeProduct name listMca-PLAC(p-OMeBz)-WAR(Dpa)-NH2

Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2

  • CAS NO.:1926163-82-7
  • Empirical Formula: C66H82N16O17S
  • Molecular Weight: 1403.52
  • MDL number: MFCD18782563
  • Update Date: 2026-04-24 14:58:35
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 Structural

What is Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2?

Description

Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).1 Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.

References

1. Eckhouse, S.R., Akerman, A.W., Logdon, C.B., et al. Differential membrane type 1 matrix metalloproteinase substrate processing with ischemia-reperfusion: Relationship to interstitial microRNA dynamics and myocardial function J. Thorac. Cardiovasc. Surg. 145(1),267-275(2013).

Properties of Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2

Density  1.47±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Formic Acid: 1 mg/ml
form  A lyophilized powder
pka 12.98±0.46(Predicted)
color  White to off-white

Safety information for Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2

Computed Descriptors for Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2

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