Lurasidone hydrochloride
- CAS NO.：367514-88-3
- Empirical Formula: C28H37ClN4O2S
- Molecular Weight: 529.14
- MDL number: MFCD18917095
- EINECS: 682-423-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-04 16:42:01
What is Lurasidone hydrochloride?
Chemical properties
Off-White Solid
The Uses of Lurasidone hydrochloride
Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively
The Uses of Lurasidone hydrochloride
An antipsychotic used for treatment of schizophrenia.
Definition
ChEBI: A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia.
Properties of Lurasidone hydrochloride
| Melting point: | 198-205°C |
| Flash point: | 9℃ |
| storage temp. | Refrigerator |
| solubility | DMSO : 10 mg/mL (18.90 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Powder |
| color | White to off-white |
Safety information for Lurasidone hydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for Lurasidone hydrochloride
| InChIKey | PQXKDMSYBGKCJA-CVTJIBDQSA-N |
| SMILES | O=C1N(C(=O)[C@@]2([H])[C@]3([H])CC[C@@]([H])(C3)[C@@]12[H])C[C@@H]1CCCC[C@H]1CN1CCN(C2=NSC3=CC=CC=C23)CC1.Cl |&1:5,7,11,14,17,22,r| |
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