liriodenine

Description

Isolated from the heartwood extract of Liriodendron tulip/era, this base may be purified by crystallization from CHCI3. It contains one methylenedioxy group and a keto group, forming a crystalline oxime, m.p. 271°C. The structure has been confirmed by synthesis, the synthetic alkaloid having a higher melting point of 287°C.

The Uses of liriodenine

Liriodenine is an isoquinoline alkaloid found in extracts of medicinal Asian vegetation such as Michelia alba and Liriodendron chinense.

Definition

ChEBI: An oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities.

References

Buchanan, Dickey.,J. Org. Chern., 25, 1389 (1960)
Taylor., Tetrahedron, 14,42 (1961)