Levofloxacin hydrochloride
- CAS NO.：100986-85-4
- Empirical Formula: C18H20FN3O4
- Molecular Weight: 361.37
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is Levofloxacin hydrochloride?
Definition
ChEBI: Levofloxacin is an optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase. It has a role as a DNA synthesis inhibitor, an antibacterial drug, a topoisomerase IV inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. It is a quinolone antibiotic, a fluoroquinolone antibiotic and a 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid. It is an enantiomer of a dextrofloxacin.
Properties of Levofloxacin hydrochloride
| Melting point: | 225-227 °C (decomp) |
| Boiling point: | 571.5±50.0 °C(Predicted) |
| Density | 1.48±0.1 g/cm3(Predicted) |
| pka | 5.19±0.40(Predicted) |
Safety information for Levofloxacin hydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Levofloxacin hydrochloride
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