LEVCROMAKALIM
- CAS NO.：94535-50-9
- Empirical Formula: C16H18N2O3
- Molecular Weight: 286.33
- MDL number: MFCD00864806
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is LEVCROMAKALIM?
The Uses of LEVCROMAKALIM
Levcromakalim is a potassium channel activator and vasorelaxant used in the management of hypertension in diabetes mellitus.
The Uses of LEVCROMAKALIM
Anti-asthmatic; antihypertensive.
What are the applications of Application
Levcromakalim is an active enantiomer of the prototypical KATP(Kir6) channel opener cromakalim
Definition
ChEBI: Levcromakalim is a 1-benzopyran.
Biological Activity
Active enantiomer of the prototypical K ATP channel opener cromakalim (trans-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile ). Hypotensive and airways relaxant. IC 50 = 490 nM in guinea pig trachea.
Storage
Store at RT
Properties of LEVCROMAKALIM
| Melting point: | 242-244° |
| Boiling point: | 482.3±45.0 °C(Predicted) |
| alpha | D26 -52.2° (c = 1 in chloroform) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | DMSO: ≤10 mM, soluble |
| form | solid |
| pka | 13.18±0.60(Predicted) |
| color | White to off-white |
Safety information for LEVCROMAKALIM
Computed Descriptors for LEVCROMAKALIM
New Products
Pentadecanoic acid 3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 2-Bromo-5-Iodopyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile Tetrahydropyranyl-4-acetic acid Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 5-Bromo-4-chloro-3-indolyl-β-D-galactopyranoside 5-fluoro-1,3-benzodioxole 2-Bromo-6-fluoroaniline 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-oneRelated products of tetrahydrofuran
![4-[3-(Dimethylamino)propoxy]benzonitrile](https://img.chemicalbook.in/CAS/GIF/146440-15-5.gif)
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