LEVCROMAKALIM
- CAS NO.：94535-50-9
- Empirical Formula: C16H18N2O3
- Molecular Weight: 286.33
- MDL number: MFCD00864806
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-30 16:22:46
What is LEVCROMAKALIM?
The Uses of LEVCROMAKALIM
Levcromakalim is a potassium channel activator and vasorelaxant used in the management of hypertension in diabetes mellitus.
The Uses of LEVCROMAKALIM
Anti-asthmatic; antihypertensive.
What are the applications of Application
Levcromakalim is an active enantiomer of the prototypical KATP(Kir6) channel opener cromakalim
Definition
ChEBI: Levcromakalim is a 1-benzopyran.
Biological Activity
Active enantiomer of the prototypical K ATP channel opener cromakalim (trans-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile ). Hypotensive and airways relaxant. IC 50 = 490 nM in guinea pig trachea.
Storage
Store at RT
Properties of LEVCROMAKALIM
| Melting point: | 242-244° |
| Boiling point: | 482.3±45.0 °C(Predicted) |
| alpha | D26 -52.2° (c = 1 in chloroform) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | DMSO: ≤10 mM, soluble |
| form | solid |
| pka | 13.18±0.60(Predicted) |
| color | White to off-white |
Safety information for LEVCROMAKALIM
Computed Descriptors for LEVCROMAKALIM
New Products
4-Iodo-3,5-dimethylbenzonitrile 2-fluoro-4-iodoaniline 2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 6,6'-methylenebis(9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one) 3-Bromo-2-fluorobenzoic acid Quinuclidine-4-carbonitrile N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 1,4-bis(methylsulfonyl)butane 4-Cyano-N-Methacryloyl-3-Trifluoromethyl Aniline 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzeneRelated products of tetrahydrofuran
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