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HomeProduct name listLercanidipine hydrochloride

Lercanidipine hydrochloride

Synonym(s):1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride

  • CAS NO.：132866-11-6
  • Empirical Formula: C36H42ClN3O6
  • Molecular Weight: 648.19
  • MDL number: MFCD07773089
  • EINECS: 603-682-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2026-03-13 09:27:42
Lercanidipine hydrochloride Structural

What is Lercanidipine hydrochloride?

Chemical properties

Pale-Yellow Powder

The Uses of Lercanidipine hydrochloride

A dihydropyridine calcium channel blocker. Antihypertensive.

The Uses of Lercanidipine hydrochloride

long-acting dihydropyridine calcium channel blocker, antihypertensive

What are the applications of Application

Lercanidipine hydrochloride hemihydrate is a Ca inhibitor

What are the applications of Application

Lercanidipine hydrochloride is a calcium channel protein inhibitor

Definition

ChEBI: Lercanidipine hydrochloride is a diarylmethane.

brand name

Cardiovasc (Recor dati, Italy); Carmen (Recordati, Italy); Corifeo (Recordati, Italy); Lercadip (Recordati, Italy); Lercan (Recordati, Italy); Lercapin (Recordati, Italy); Lercaton (Recordati, Italy); Lerkamen (Recordati, Italy); Lerzam (Recordati, Italy); Renovia (Recordati, Italy); Vasodip (Recordati, Italy); Zandip (Recordati, Italy); Zanicor (Recordati, Italy).

Biological Activity

L-type Ca 2+ channel blocker that displays higher vascular selectivity than Felodipine (4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester ). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive.

Biochem/physiol Actions

Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.

Properties of Lercanidipine hydrochloride

Melting point: 175-177°C
storage temp.  2-8°C
solubility  soluble in Methanol
form  powder
color  yellow
Merck  14,5446
CAS DataBase Reference 132866-11-6(CAS DataBase Reference)

Safety information for Lercanidipine hydrochloride

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
Precautionary Statement Codes P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for Lercanidipine hydrochloride

InChIKey WMFYOYKPJLRMJI-UHFFFAOYSA-N

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