laudanosine
- CAS NO.：2688-77-9
- Empirical Formula: C21H27NO4
- Molecular Weight: 357.44
- MDL number: MFCD27978049
- EINECS: 220-253-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:30:36
What is laudanosine ?
The Uses of laudanosine
Laudanosine is a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
Definition
ChEBI: Laudanosine is a member of isoquinolines.
Purification Methods
Crystallise these from EtOH. The (±)-picrate crystallises from EtOH with m 177-178o. The (-)-isomer has m 83-85o and
Properties of laudanosine
| Melting point: | 89° |
| Boiling point: | 490.07°C (rough estimate) |
| alpha | D16 +106° (c = 1.6 in 97% alc); D16 +130° (chloroform); D22 +52.2 ±1.3° (chloroform); D20 +82.5° (ethanol) |
| Density | 1.1729 (rough estimate) |
| refractive index | 1.5614 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly, Sonicated) |
| form | White to Pale Beige |
| pka | 7.80±0.40(Predicted) |
Safety information for laudanosine
Computed Descriptors for laudanosine
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
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