Mc-Val-Cit-PABC-PNP
- CAS NO.：159857-81-5
- Empirical Formula: C35H43N7O11
- Molecular Weight: 737.76
- MDL number: MFCD22200431
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-26 18:10:20
What is Mc-Val-Cit-PABC-PNP?
Description
Mc-Val-Cit-PABC-PNP is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to anticancer compounds, such as doxorubicin or monomethyl auristatin E (MMAE; ). ADCs target specific cell populations to induce a selective response, such as cell death in cancer cells.
The Uses of Mc-Val-Cit-PABC-PNP
Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates.
Properties of Mc-Val-Cit-PABC-PNP
| Boiling point: | 1034.5±65.0 °C(Predicted) |
| Density | 1.338±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMF: 25 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH 7.2) (1:4): 0.20 mg/ml |
| form | A crystalline solid |
| pka | 13.24±0.70(Predicted) |
| color | Off-white to light yellow |
Safety information for Mc-Val-Cit-PABC-PNP
Computed Descriptors for Mc-Val-Cit-PABC-PNP
New Products
4,4-Difluoropiperidine hydrochloride tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin N-Isopropylurea N,N-Dicyclohexylcarbodiimide(DCC) MELDRUMS ACID 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID Magnessium Bis glycinate Zinc ascorbate 1-bromo-2-butyne 2-acetamidophenol 9(10H)-anthracenone Erythrosin B, 4-Piperidinopiperidine 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 2-(benzylamino)acetic acid hydrochloride 4-(tert-Butoxycarbonylamino)but- 2-ynoic acid 3,4-dihydro-2H-benzo[b][1,4]dioxepine 1-Phenyl-1-cycloprppanecarboxylicacidRelated products of tetrahydrofuran
You may like
-
159857-81-5 98%View Details
159857-81-5 -
N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-L-ornithinamide 98%View Details
159857-81-5 -
159857-81-5 Mc-Val-Cit-PABC-PNP 98%View Details
159857-81-5 -
Mc-Val-Cit-PABC-PNP 98%View Details
159857-81-5 -
Mc-Val-Cit-PABC-PNP 159857-81-5 98%View Details
159857-81-5 -
Mc-val-cit-pabc-pnp 95% CAS 159857-81-5View Details
159857-81-5 -
20677-73-0 (2,2-diethoxyethyl)methylamine 98%View Details
20677-73-0 -
3-(4-(hydroxyamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione 98%View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.