L-KAWAIN
- CAS NO.：500-64-1
- Empirical Formula: C14H14O3
- Molecular Weight: 230.26
- MDL number: MFCD00467093
- EINECS: 207-907-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 09:27:42
What is L-KAWAIN?
Originator
Largon,Klinge
The Uses of L-KAWAIN
Kawain is a plant extract that shows antioxidant activity through cyclooxygenase enzyme inhibition. May also be active in tumor suppression and apoptotic induction.
What are the applications of Application
Kavain (±) is a biologically active component of kava that blocks various cationic voltage-gated channels
Definition
ChEBI: Kawain is a member of 2-pyranones and an aromatic ether.
Manufacturing Process
To 1170 g ethyl acetoacetate at 100-110°C was added a little at time 1605 g
bromosuccinimide. After cooling to the mixture was added 300 ml of carbon
tetrachloride. From the mixture was isolated ethyl ester of bromoacetoacetic
acid which was distilled at 105-125°C/18 mm; yield 67%.
By condensation of the mixture 1400 g ethyl ester of bromoacetoacetic acid,
700 g bromosuccineimide, 500 ml benzene and 350 mg zinc was prepared
(R)-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one; melting point 157°C,
yield 60-70%.
Therapeutic Function
Anesthetic; Tranquilizer
Properties of L-KAWAIN
| Melting point: | 142-148℃ |
| Boiling point: | bp0.1 195-197° |
| alpha | D20 +105° (abs alc) |
| Density | 1.1914 (rough estimate) |
| refractive index | 1.5557 (estimate) |
| storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| color | White to Light Yellow |
| Stability: | Light Sensitive |
Safety information for L-KAWAIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for L-KAWAIN
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline 5-Hydroxy-3,9-dimethyl-7H-benzo[c]fluoren-7-one Methyl 4-(acetyloxy)-6-methoxy-1-(4-methoxyphenyl)-2naphthalenecarboxylate 4-Hydroxy-6,7-dimethoxy-1-phenyl-2naphthalenecarboxylic acid (3,5-Dibromophenyl)[4-(trifluoromethyl)phenyl]methanone (4-butoxyphenyl)(4-fluorophenyl)methanone (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity Benzyl-N,4-dimethylpiperidine-3- amine dihydrochloride 3-(4-phenoxyphenyl)-1H- pyrazolo[3,4- d]pyrimidin-4- amine 4-Ethyl-4-hydroxy-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione (E)-N'-(2-cyano-4-nitrophenyl)- N,N-dimethylformimidamide N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide 5-bromopyridin-2-amine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
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