L-Anserine

CAS NO.：584-85-0
Empirical Formula: C10H16N4O3
Molecular Weight: 240.26
MDL number: MFCD11040910
EINECS: 209-545-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-16 07:06:08

What is L-Anserine?

Definition

ChEBI: Anserine is a dipeptide comprising of beta-alanine and 3-methyl-L-histidine units. It has a role as an animal metabolite and a mouse metabolite. It is a beta-alanine derivative and a dipeptide. It is a tautomer of an anserine zwitterion.

Purification Methods

Crystallise anserine from aqueous EtOH. It is hygroscopic and is best stored as the nitrate salt (see below). Purify it by shaking the nitrate salt with Dowex 3 (x4 free base) and washing with H2O, evaporating the filtrate and removing H2O by 3 distillations with 10mL of propan-2-ol. Dissolve the crystals in MeOH and add H2O dropwise until one phase is obtained and cool. Dry the crystals at 60o over P2O5 in a vacuum. The picrate has m 145o (from H2O). [Rinderknecht et al. J Org Chem 29 1968 1964, Beilstein 25 II 408, 25 IV 4383.]

Properties of L-Anserine

Melting point:	268℃ (decomposition)
Boiling point:	611.3±55.0 °C(Predicted)
Density	1.38±0.1 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
solubility	Methanol (Slightly, Heated), Water (Slightly)
form	Solid
pka	3.02±0.10(Predicted)
color	White to Off-White

Safety information for L-Anserine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.