Kushenol K
- CAS NO.：101236-49-1
- Empirical Formula: C26H32O8
- Molecular Weight: 472.53
- MDL number: MFCD31579630
- Update Date: 2026-01-03 20:00:36
What is Kushenol K?
Biological Activity
Kushenol K, a flavonoid antioxidant from Sophora flavescens. It can inhibit the activity of SGLT1 and SGLT2 and used as an inhibitor of CYP3A4 with a Ki value of 1.35 μM.
in vivo
When Midazolam is used as the substrate of CYP3A4, Kushenol K exhibits the strong inhibition with an IC 50 values of 1.62 μM.
At a concentration of 50 μM, the The inhibition rate of Kushenol K on SGLT1 is 29.7%, and the inhibition rate on SGLT2 is 43.7%.
Properties of Kushenol K
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
Safety information for Kushenol K
Computed Descriptors for Kushenol K
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