Kuguacin J
- CAS NO.：1141453-65-7
- Empirical Formula: C30H46O3
- Molecular Weight: 454.68
- MDL number: MFCD25371936
- Update Date: 2023-07-14 17:48:18
What is Kuguacin J?
Description
Kuguacin J exerts growth inhibition through G1 arrest and induction of apoptosis in androgen-dependent human prostate cancer, it is a promising candidate new antineoplastic and chemopreventive agent for androgen-dependent prostate cancer and carcinogenesis. Kuguacin J modulates the function of P-glycoprotein (P-gp) by directly interacting at the drug-substrate-binding site, and it appears to be an effective inhibitor of P-gp activity in vitro and thus could be developed as an effective chemosensitizer to treat multidrug-resistant cancers.
Properties of Kuguacin J
| Melting point: | 166-169 °C |
| Boiling point: | 563.7±50.0 °C(Predicted) |
| Density | 1.07±0.1 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 13.73±0.70(Predicted) |
Safety information for Kuguacin J
Computed Descriptors for Kuguacin J
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