Kuguacin J

CAS NO.：1141453-65-7
Empirical Formula: C30H46O3
Molecular Weight: 454.68
MDL number: MFCD25371936
Update Date: 2023-07-14 17:48:18

What is Kuguacin J?

Description

Kuguacin J exerts growth inhibition through G1 arrest and induction of apoptosis in androgen-dependent human prostate cancer, it is a promising candidate new antineoplastic and chemopreventive agent for androgen-dependent prostate cancer and carcinogenesis. Kuguacin J modulates the function of P-glycoprotein (P-gp) by directly interacting at the drug-substrate-binding site, and it appears to be an effective inhibitor of P-gp activity in vitro and thus could be developed as an effective chemosensitizer to treat multidrug-resistant cancers.

Properties of Kuguacin J

Melting point:	166-169 °C
Boiling point:	563.7±50.0 °C(Predicted)
Density	1.07±0.1 g/cm3(Predicted)
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	13.73±0.70(Predicted)

Safety information for Kuguacin J

Computed Descriptors for Kuguacin J

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