KRH 102053
- CAS NO.：1353254-53-1
- Empirical Formula: C25H34N2O5S
- Molecular Weight: 474.61
- Update Date: 2026-01-05 11:31:08
What is KRH 102053?
Description
KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 and monocarboxylate transporter 4. Consistent with these results, KRH102053 also inhibited the rates of HIF-related migration and invasion of HOS cells as well as the degree of tube formation in human umbilical vein endothelium cells.
Properties of KRH 102053
| Boiling point: | 599.2±50.0 °C(Predicted) |
| Density | 1.21±0.1 g/cm3(Predicted) |
| pka | 6.70±0.35(Predicted) |
Safety information for KRH 102053
Computed Descriptors for KRH 102053
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