KPT-8602
- CAS NO.：1642300-52-4
- Empirical Formula: C17H10F6N6O
- Molecular Weight: 428.3
- MDL number: MFCD30489739
- Update Date: 2026-04-17 10:13:23
What is KPT-8602?
The Uses of KPT-8602
(αE)?-α-?[[3-?[3,?5-?bis(Trifluoromethyl)?phenyl]?-?1H-?1,?2,?4-?triazol-?1-?yl]?methylene]?-?5-pyrimidineacetamide is an exportin-1 inhibitor with anti-leukemic activity. Exportin-1 mediates nuclear trafficking of proteins. (αE)?-α-?[[3-?[3,?5-?bis(Trifluoromethyl)?phenyl]?-?1H-?1,?2,?4-?triazol-?1-?yl]?methylene]?-?5-pyrimidineacetamide can be used to develop treatments for acute lymphoblastic leukemia.
Properties of KPT-8602
| Boiling point: | 574.4±60.0 °C(Predicted) |
| Density | 1.57±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 13.06±0.50(Predicted) |
| color | Off-white to light yellow |
Safety information for KPT-8602
Computed Descriptors for KPT-8602
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