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HomeProduct name listKP372-1

KP372-1

Synonym(s):10H-Indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one (1:1);6H-Indeno[1,2-e]tetrazolo[1,5-b][1,2,4]triazin-6-one

KP372-1 Structural

What is KP372-1?

The Uses of KP372-1

KP372-1 is a specific Akt inhibitor that demonstrates at least 10-fold selectivity against a panel of additional kinase targets, including CDK1, ERK1, GSK3β, LCK, MEK1, PKA, PKC, and S6K. By blocking Akt signaling, KP372-1 has been shown to inhibit proliferation and to induce apoptosis of thyroid cancer cells.

Properties of KP372-1

Density  2.01±0.1 g/cm3(Predicted)
pka -3.26±0.20(Predicted)

Safety information for KP372-1

Computed Descriptors for KP372-1

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