K811
- CAS NO.：1355228-38-4
- Empirical Formula: C29H26N4O5
- Molecular Weight: 510.54
- MDL number: MFCD32697116
- Update Date: 2026-05-11 15:21:01
What is K811?
Description
K811 is an ASK1-specific inhibitor that prolongs survival in a mouse model of amyotrophic lateral sclerosis. K811 efficiently prevented cell proliferation in cell lines with high ASK1 expression and in HER2-overexpressing GC cells. Treatment with K811 reduced sizes of xenograft tumors by downregulating proliferation markers.
Properties of K811
| Density | 1.326±0.06 g/cm3(Predicted) |
| pka | 11.33±0.70(Predicted) |
Safety information for K811
Computed Descriptors for K811
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