JWH 122-d9

Description

JWH 122-d₉ is intended for use as an internal standard for the quantification of JWH 122 by GC- or LC-MS. JWH 122 is a synthetic cannabinoid (CB) that displays high-affinities for both CB₁ (K_i = 0.69 nM) and CB₂ (K_i = 1.2 nM) receptors.^1,2 JWH 122-d₉ is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

References

1. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB₁ and CB₂ receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB₂ receptor agonists Bioorg. Med. Chem. 13(1),89-112(2005).
2. Huffman, J.W., Mabon, R., Wu, M.J., et al. 3-indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB₁ cannabinoid receptor Bioorgan. Med. Chem. 11(4),539-549(2003).