Jingzhaotoxin III
- CAS NO.:925463-91-8
- Empirical Formula: C174H241N47O46S6
- Molecular Weight: 0
- Update Date: 2025-06-18 16:39:36
What is Jingzhaotoxin III?
Description
Selective blocker of NaV5 channels (IC50 = 348 nM); displays no effect on other isoforms, including NaV2, NaV4, NaV6 and NaV7. Thought to inhibit sodium channel activation by binding to the NaV5 S3-S4 linker of domain II. Selectively inhibits the activation of cardiac sodium channels, but has no effect on sodium channels in dorsal root ganglion neurons.
Storage
Store at -20°C
Properties of Jingzhaotoxin III
| storage temp. | Store at -20°C |
| form | Powder |
| Water Solubility | Soluble to 1 mg/ml in water |
Safety information for Jingzhaotoxin III
Computed Descriptors for Jingzhaotoxin III
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