Isobutylmercaptan

Chemical properties

Liquid; unpleasant odor.

Chemical properties

2-Methyl-1-propanethiol has a cooked vegetable, almost mustard-like, odor

Occurrence

Reported found in guava, milk, cooked beef, cooked pork and beer.

The Uses of Isobutylmercaptan

Flammable, dangerous fire risk.

What are the applications of Application

2-Methyl-1-propanethiol is used in the study of drug delivery and self-assembling monolayers

General Description

2-methyl-1-propanethiol attaches with L-Cys (the carrier) via a disulfide bond to form the brain-targeted drug delivery systems (BTDS).

Purification Methods

Dissolve the thiol in EtOH, and add to 0.25M Pb(OAc)2 in 50% aqueous EtOH. The precipitated lead mercaptide is filtered off, washed with a little EtOH, and impurities are removed from the molten salt by steam distillation. After cooling, dilute HCl is added dropwise to the residue, and the mercaptan is distilled directly from the flask. Water is separated from the distillate, and the mercaptan is dried (Na2CO3) and distilled under nitrogen. [Mathias J Am Chem Soc 72 1897 1950, Beilstein 1 H 378, 1 I 191, 1 II 412, 1 III 1565, 1 IV 1605.]