Iron(III) citrate
Synonym(s):Ferric citrate;Iron(III) citrate;Iron(III) citrate hydrate
- CAS NO.：3522-50-7
- Empirical Formula: C6H8FeO7
- Molecular Weight: 247.97
- MDL number: MFCD00013098
- EINECS: 222-536-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-15 13:03:24
What is Iron(III) citrate?
Description
Ferric citrate (iron (III) citrate) is prepared from reaction of citric acid with ferric hydroxide. It is a compound of indefinite ratio of citric acid and iron. Ferric citrate is slowly soluble in cold water, readily soluble in hot water, and practically insoluble in alcohol.
Chemical properties
solid
The Uses of Iron(III) citrate
Iron(III) Citrate is an integral part of the structural basis of gating by the outer membrane receptor FecA from Escherichia coli. Binding of ferric citrate triggers a conformational change of the extracellular loops that close the external pocket of FecA.
Biochem/physiol Actions
Ferric citrate is used as a component of protein-free medium. It is used as a substitute for transferrin in mouse hybridomas culture. Ferric citrate enhances IgM production. It indirectly stimulates the mitogen-activated protein kinase (MAPK) by favoring high amphiregulin oncoprotein levels in colon cancer.? Ferric citrate is effective in binding to phosphate in patients with dialysis-dependent chronic kidney disease.
Properties of Iron(III) citrate
| Melting point: | >300°C |
| storage temp. | room temp |
| solubility | soluble in H2O; insoluble in ethanol |
| form | red-brown crystals |
| color | Dark Orange to Very Dark Orange |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 3522-50-7(CAS DataBase Reference) |
Safety information for Iron(III) citrate
Computed Descriptors for Iron(III) citrate
| InChIKey | NPFOYSMITVOQOS-UHFFFAOYSA-K |
Iron(III) citrate manufacturer
Vasa Pharmachem Pvt Ltd. (VPPL)
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