IRL-1620
- CAS NO.:142569-99-1
- Empirical Formula: C86H117N17O27
- Molecular Weight: 1820.95
- MDL number: MFCD00214284
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is IRL-1620?
Biological Activity
IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM.
in vitro
IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900).
Storage
-20°C (desiccate)
Properties of IRL-1620
| Boiling point: | 2096.6±65.0 °C(Predicted) |
| Density | 1.347±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Soluble in DMSO |
| form | powder |
| pka | 3.39±0.10(Predicted) |
| color | white |
| Water Solubility | Soluble in water (0.5 mg/ml) |
Safety information for IRL-1620
Computed Descriptors for IRL-1620
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Dipropyl disulfide Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran






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