IRL-1620
- CAS NO.：142569-99-1
- Empirical Formula: C86H117N17O27
- Molecular Weight: 1820.95
- MDL number: MFCD00214284
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is IRL-1620?
Biological Activity
IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM.
in vitro
IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900).
Storage
-20°C (desiccate)
Properties of IRL-1620
| Boiling point: | 2096.6±65.0 °C(Predicted) |
| Density | 1.347±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Soluble in DMSO |
| form | powder |
| pka | 3.39±0.10(Predicted) |
| color | white |
| Water Solubility | Soluble in water (0.5 mg/ml) |
Safety information for IRL-1620
Computed Descriptors for IRL-1620
New Products
6-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridine 4-FLUOROBENZOYLACETONITRILE (S)-Glycidyl Phthalimide Maleic hydrazide 8-Bromo-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 4'-Hydroxyacetophenone 3-Bromophenylacetic acid Tridecanoic acid Pentadecanoic acid 3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Hendecanoic acid 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 4-pyridine methanol Ethyl 3,3- diethoxypropionate 5-Bromo-pyridine-2-carbaldehyde 1-Bromo-3-phenylpropane 4-(4-Methylpiperazino)aniline 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate N-((S)-1-(3-(3-amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate 4-bromo-2-ethyl-3-fluorobenzoic acid 6-(chloromethyl)pteridine-2,4-diamine monohydrochloride 2-Chlorophenyl diphenyl chloromethaneRelated products of tetrahydrofuran
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