irisolidone
- CAS NO.：2345-17-7
- Empirical Formula: C17H14O6
- Molecular Weight: 314.29
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is irisolidone?
Description
Irisolidone is a hydrolyzed product of kudzurin. Studies have shown that it can significantly dilate coronary arteries, cerebral arteries and peripheral blood vessels and microvessels, and can reduce vascular resistance, cholesterol and blood viscosity.
Chemical properties
Light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from kudzu.
The Uses of irisolidone
Irisolidone has anti-inflammatory, antioxidant, antibacterial, anti-tumor, estrogen-like effects, and protects liver damage caused by alcoholism.
Definition
ChEBI: Irisolidone is a member of 4'-methoxyisoflavones.
Biological Activity
Irisolidone is the main isoflavone in pueraria. Irisolidone has strong hepatoprotective activity. It has a highly effective blocking effect on the anion channel VRAC.
in vitro
Irisolidone shows the high efficacy for Volume-regulated anion channels (VRAC) blockade with an IC 50 of 9.8 μM in HEK293 cells.
It can inhibit endothelial cell proliferation.
Properties of irisolidone
| Melting point: | 190-191 °C |
| Boiling point: | 565.5±50.0 °C(Predicted) |
| Density | 1.402±0.06 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| solubility | Chloroform (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 6.48±0.20(Predicted) |
| color | Off-White to Pale Yellow |
Safety information for irisolidone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for irisolidone
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