INSULIN CHAIN B, OXIDIZED

The Uses of INSULIN CHAIN B, OXIDIZED

Insulin Chain B Oxidized from bovine pancreas has been used:

• as a matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry (MS) calibration standard
• in electrochemical impedance spectroscopy and quartz crystal nanobalance (EQCN) studies of insulin adsorption on platinum
• as an internal standard to quantify insulin chain B residue in protein samples

General Description

Insulin is made up of two polypeptide chains (A and B) linked together by two disulfide linkages. Chain A and B are composed of 21 amino acids and 30 amino acids, respectively.

Biochem/physiol Actions

Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids. It inhibits the breakdown of glycogen, protein, and fat. The β chain is a substrate for carboxypeptidase Y.