INDOLE-3-GLYOXYLYL CHLORIDE
Synonym(s):α-Oxoindole-3-acetyl chloride;2-(3-Indolyl)-2-oxoacetyl chloride;NSC 128332
- CAS NO.：22980-09-2
- Empirical Formula: C10H6ClNO2
- Molecular Weight: 207.61
- MDL number: MFCD00015460
- EINECS: 245-362-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:22:18
What is INDOLE-3-GLYOXYLYL CHLORIDE?
The Uses of INDOLE-3-GLYOXYLYL CHLORIDE
INDOLE-3-GLYOXYLYL CHLORIDE is an indole derivative used in the preparation of reagents for chemiluminescent enzyme immunoassay. It is an impurity in the manufacture of tryptamines and related compounds.
The Uses of INDOLE-3-GLYOXYLYL CHLORIDE
• ;Reactant for preparation of dual IGF-1R/SRC inhibitors1• ;Reactant for preparation of indolylglyoxylamides as a new class of antileishmanial agents2• ;Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents3• ;Reactant for diastereoselective synthesis of heptacyclic core of dragmacidin E4• ;Reactant for preparation of benzoylmethylpyrrolopyridinylethanedione as HIV-1 inhibitor5• ;Reactant for preparation of fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D16
The Uses of INDOLE-3-GLYOXYLYL CHLORIDE
- Reactant for preparation of dual IGF-1R/SRC inhibitors
- Reactant for preparation of indolylglyoxylamides as a new class of antileishmanial agents
- Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents
- Reactant for diastereoselective synthesis of heptacyclic core of dragmacidin E
- Reactant for preparation of benzoylmethylpyrrolopyridinylethanedione as HIV-1 inhibitor
- Reactant for preparation of fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1
What are the applications of Application
3-Indoleglyoxylyl chloride is Useful in the preparation of a variety ofinhibitors
Properties of INDOLE-3-GLYOXYLYL CHLORIDE
| Melting point: | 138 °C (dec.) (lit.) |
| Boiling point: | 413.9±37.0 °C(Predicted) |
| Density | 1.463±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 14.29±0.30(Predicted) |
| Sensitive | Moisture Sensitive |
| BRN | 147693 |
| CAS DataBase Reference | 22980-09-2(CAS DataBase Reference) |
Safety information for INDOLE-3-GLYOXYLYL CHLORIDE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for INDOLE-3-GLYOXYLYL CHLORIDE
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