DBCO-PEG4-VA-PBD[DBCO-PEG4-VA-PBD

CAS NO.：2241644-09-5
Empirical Formula: C80H87N9O16
Molecular Weight: 1430.6
Update Date: 2025-04-17 18:22:24

What is DBCO-PEG4-VA-PBD[DBCO-PEG4-VA-PBD?

Biological Activity

DBCO-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Properties of DBCO-PEG4-VA-PBD[DBCO-PEG4-VA-PBD

Density	1.30±0.1 g/cm3(Predicted)
pka	13.55±0.70(Predicted)
form	Solid
color	White to light yellow

Safety information for DBCO-PEG4-VA-PBD[DBCO-PEG4-VA-PBD

Computed Descriptors for DBCO-PEG4-VA-PBD[DBCO-PEG4-VA-PBD

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