1H-Pyrazole-5-carboxamide, N-[(1S)-1-[[[4-(3,5-dimethoxy-1-oxido-4-pyridinyl)phenyl]amino]carbonyl]-2,2-diphenylethyl]-1-methyl-

CAS NO.：2748749-47-3
Empirical Formula: C33H31N5O5
Molecular Weight: 577.63
Update Date: 2026-04-24 14:58:19

What is 1H-Pyrazole-5-carboxamide, N-[(1S)-1-[[[4-(3,5-dimethoxy-1-oxido-4-pyridinyl)phenyl]amino]carbonyl]-2,2-diphenylethyl]-1-methyl-?

Biological Activity

IL-17A modulator-2 is a IL-17A modulator, extracted from patent WO2021239743+A1, example 27. IL-17A modulator-2 inhibits the biological action of IL-17A with a pIC50 of 8.3. IL-17A modulator-2 can be used for the research of diseases or disorders associated with modulation of IL-17A activity including diseases with an immune component or autoimmune pathol, cancer and neurodegenerative disorders[1].

References

[1]. Barrie Phillip MARTIN, et al. Preparation of amino acid amides as IL-17A modulators. WO2021239743 A1.

Properties of 1H-Pyrazole-5-carboxamide, N-[(1S)-1-[[[4-(3,5-dimethoxy-1-oxido-4-pyridinyl)phenyl]amino]carbonyl]-2,2-diphenylethyl]-1-methyl-

Boiling point:	893.3±65.0 °C(Predicted)
Density	1.26±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
form	Solid
pka	12.60±0.46(Predicted)
color	White to off-white

Safety information for 1H-Pyrazole-5-carboxamide, N-[(1S)-1-[[[4-(3,5-dimethoxy-1-oxido-4-pyridinyl)phenyl]amino]carbonyl]-2,2-diphenylethyl]-1-methyl-

Computed Descriptors for 1H-Pyrazole-5-carboxamide, N-[(1S)-1-[[[4-(3,5-dimethoxy-1-oxido-4-pyridinyl)phenyl]amino]carbonyl]-2,2-diphenylethyl]-1-methyl-

New Products

2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one