C16 Ganglioside GM2-d9 (d18:1/16:0-d9) (ammonium salt)

Description

C16 Ganglioside G_M2-d₉ (d18:1/16:0-d₉) is intended for use as an internal standard for the quantification of C16 ganglioside G_M2 by GC- or LC-MS. C16 Ganglioside G_M2 (d18:1/16:0) is a monosialated ganglioside.¹ It has been found in A2780 ovarian carcinoma cells, as well as purified ganglioside mixtures extracted from healthy postmortem and hemangioma-bearing human frontal lobe cortical tissue.^1,2 As this product is derived from a natural source, there may be variations in the sphingoid backbone.

References

1. Schiopu, C., Flangea, C., Capitan, F., et al. Determination of ganglioside composition and structure in human brain hemangioma by chip-based nanoelectrospray ionization tandem mass spectrometry Anal. Bioanal. Chem. 395(8),2465-2477(2009).
2. Valsecchi, M., Aureli, M., Mauri, L., et al. Sphingolipidomics of A2780 human ovarian carcinoma cells treated with synthetic retinoids J. Lipid Res. 51(7),1832-1840(2010).