INDATRALINE HYDROCHLORIDE
Synonym(s):(±)-trans-3-(3,4-Dichlorophenyl)-N-methyl-1-indanamine hydrochloride;Lu 19-005
- CAS NO.：96850-13-4
- Empirical Formula: C16H16Cl3N
- Molecular Weight: 328.66
- MDL number: MFCD00083178
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is INDATRALINE HYDROCHLORIDE?
The Uses of INDATRALINE HYDROCHLORIDE
Indatraline Hydrochloride?inhibits the synaptosomal uptake of 3,4-dihydroxyphenylethylamine (dopamine, DA), noradrenaline (NA), and 5-hydroxytryptamine (5-HT, serotonin).
The Uses of INDATRALINE HYDROCHLORIDE
Indatraline hydrochloride has been used:
- as a competitive inhibitor of 3H-dopamine ([3H]DA) to study its effects on trans-activator of transcription (Tat) protein on cocaine-induced inhibition of uptake of [3H]DA
- as a dopamine transport blocker to study its effects on trace amine-associated receptor 1 (TAAR1)-transfected mice cells
- as a nonselective monoamine transport inhibitor to study its anti-angiogenic activities in glioblastoma multiforme (GBM)
What are the applications of Application
Indatraline hydrochloride is an inhibitor of ST, DAT, and SLC6A2
Biochem/physiol Actions
Indatraline is a non-selective monoamine transport inhibitor. It inhibits the reuptake of neurotransmitters, such as serotonin, norepinephrine and dopamine. It exhibits anti-depressant and anti-angiogenic effects. Indatraline also plays a role in inducing autophagy.
Storage
Desiccate at RT
Properties of INDATRALINE HYDROCHLORIDE
| storage temp. | 2-8°C |
| solubility | 0.1 M HCl: 1 mg/mL |
| form | solid |
| color | white |
Safety information for INDATRALINE HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Environment GHS09 |
| GHS Hazard Statements |
H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for INDATRALINE HYDROCHLORIDE
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