IDO-IN-6

CAS NO.：1402837-76-6
Empirical Formula: C18H21FN2O2
Molecular Weight: 316.38
MDL number: MFCD30207887
Update Date: 2026-04-21 10:31:43

What is IDO-IN-6?

Description

IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.

IDO-IN-6 (Compound 1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of <1 μM (this is the concentration of IDO-IN-6 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].

References

[1]. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.

Properties of IDO-IN-6

Boiling point:	555.4±35.0 °C(Predicted)
Density	1.42±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 50 mg/mL (158.04 mM)
pka	14.66±0.20(Predicted)
form	Solid
color	White to off-white

Safety information for IDO-IN-6

Computed Descriptors for IDO-IN-6

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