IDH1 Inhibitor 2
- CAS NO.：2244895-42-7
- Empirical Formula: C26H22N4O
- Molecular Weight: 406.48
- MDL number: MFCD32067987
- Update Date: 2026-04-21 10:31:43
What is IDH1 Inhibitor 2?
Description
IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1]. IC50: 110 nM (IDH1)[1].
References
[1]. Jakob CG, et al. Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J Med Chem. 2018 Aug 9;61(15):6647-6657.
Properties of IDH1 Inhibitor 2
| Boiling point: | 549.4±60.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 2.90±0.70(Predicted) |
| form | Solid |
| color | White to yellow |
Safety information for IDH1 Inhibitor 2
Computed Descriptors for IDH1 Inhibitor 2
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