Hydroxyprogesterone acetate
Synonym(s):17α-Acetoxy-4-pregnene-3,20-dione;17α-Acetoxyprogesterone;17α-Hydroxy-4-pregnene-3,20-dione 17-acetate;17α-Hydroxyprogesterone 17-acetate;4-Pregnen-17α-ol-3,20-dione acetate
- CAS NO.：302-23-8
- Empirical Formula: C23H32O4
- Molecular Weight: 372.5
- MDL number: MFCD00021152
- EINECS: 206-119-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is Hydroxyprogesterone acetate?
Chemical properties
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The Uses of Hydroxyprogesterone acetate
An impurity in steroid drug Megestrol acetate (M208050).
The Uses of Hydroxyprogesterone acetate
Progesterone Acetate (Megestrol Acetate EP Impurity K) is an impurity in steroid drug Megestrol acetate (M208050).
Properties of Hydroxyprogesterone acetate
| Melting point: | 249-250°C |
| Boiling point: | 421.94°C (rough estimate) |
| Density | 1.0415 (rough estimate) |
| refractive index | 1.4433 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Sparingly) |
| form | neat |
| Water Solubility | 1.01mg/L at 20℃ |
| λmax | 241nm(EtOH)(lit.) |
| BRN | 2227870 |
| InChI | InChI=1S/C23H32O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h13,18-20H,5-12H2,1-4H3/t18-,19+,20+,21+,22+,23+/m1/s1 |
| CAS DataBase Reference | 302-23-8(CAS DataBase Reference) |
Safety information for Hydroxyprogesterone acetate
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H351:Carcinogenicity |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Hydroxyprogesterone acetate
| InChIKey | VTHUYJIXSMGYOQ-KOORYGTMSA-N |
| SMILES | C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](OC(C)=O)(C(=O)C)CC3)CC2 |
Hydroxyprogesterone acetate manufacturer
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