HYDROXYNAPHTHOL BLUE
Synonym(s):2,2′-Dihydroxy-1,1′-azonaphthalene-3′,4,6′-trisulfonic acidtrisodiumsalt;calcium;Hydroxynaphthol Blue;See Other Information (Section 15)
- CAS NO.：63451-35-4
- Empirical Formula: C20H15N2NaO11S3
- Molecular Weight: 578.51
- MDL number: MFCD00036393
- EINECS: 264-197-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:18
What is HYDROXYNAPHTHOL BLUE?
Chemical properties
blue crystalline powder
The Uses of HYDROXYNAPHTHOL BLUE
Hydroxynapthol Blue is a pharmaceutical dye used in colorimetric analyses.
Purification Methods
The crude material is treated with hot EtOH to remove soluble impurities, then dissolve in 20% aqueous MeOH and chromatographed on a cellulose powder column with propanol/EtOH/water (5:5:4) as eluent. The upper of three zones was eluted to give the pure dye which is precipitated as the monosodium salt trihydrate by adding conc HCl to the concentrated eluate [Ito & Ueno Analyst 95 583 1970]. It can be converted to the trisodium salt wih the calculated amount of alkali. Indigocarmine (2[1,3-dihydro-3-oxo-5-sulfo-2H -indol-2-ylidene]-2,3-dihydro-3-oxo-1H -
Properties of HYDROXYNAPHTHOL BLUE
| storage temp. | Store at +15°C to +30°C. |
| solubility | 340g/l |
| form | Solid |
| color | Dark Gray |
| PH | 2-3 (10g/l, H2O, 20℃) |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 63451-35-4(CAS DataBase Reference) |
| EPA Substance Registry System | 2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-[(2-hydroxy-4-sulfo-1-naphthalenyl)azo]-, trisodium salt (63451-35-4) |
Safety information for HYDROXYNAPHTHOL BLUE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for HYDROXYNAPHTHOL BLUE
HYDROXYNAPHTHOL BLUE manufacturer
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