Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)

CAS NO.：1854126-47-8
Empirical Formula: C16H22ClN3O
Molecular Weight: 307.82
Update Date: 2025-04-17 18:22:24

What is Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)?

Biological Activity

Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1 It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.

References

1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018)

Properties of Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)

storage temp.	Store at -20°C
solubility	DMF: Soluble,DMSO: Soluble,Methanol: Soluble
form	A solid

Safety information for Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)

Computed Descriptors for Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)

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