Hydrocortisone IMpurity I
- CAS NO.：103795-84-2
- Empirical Formula: C21H30O6
- Molecular Weight: 378.46
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-21 16:56:50
What is Hydrocortisone IMpurity I?
The Uses of Hydrocortisone IMpurity I
14α-Hydroxycortisol (Hydrocortisone EP Impurity I) is an impurity of Hydrocortisone (H714615), a topical corticosteroid (1), but more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
Properties of Hydrocortisone IMpurity I
| Melting point: | 241-242 °C |
| Boiling point: | 602.3±55.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| pka | 12.10±0.70(Predicted) |
Safety information for Hydrocortisone IMpurity I
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Hydrocortisone IMpurity I
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