HUMAN VEGF165
Synonym(s):VEGF;VEGFA;vascular endothelial growth factor A;Vascular Endothelial Growth Factor-A;Vascular permeability factor
- CAS NO.：127464-60-2
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00286542
- Update Date: 2026-01-13 11:14:16
What is HUMAN VEGF165?
The Uses of HUMAN VEGF165
VEGF human has been used as a chemoattractant for HUVECs (human umbilical vein endothelial cells) migration assay.
General Description
VEGF (vascular endothelial growth factor) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Biochem/physiol Actions
VEGF (vascular endothelial growth factor) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intraocular neovascular syndromes. Polymorphism in VEGF at C(-634)G is linked with diabetic retinopathy in type 2 diabetes.
Properties of HUMAN VEGF165
| storage temp. | -20°C |
| form | powder |
| color | white |
Safety information for HUMAN VEGF165
Computed Descriptors for HUMAN VEGF165
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