Heronapyrrole B

CAS NO.：1255704-24-5
Empirical Formula: C19H32N2O6
Molecular Weight: 384.47
Update Date: 2023-05-21 10:59:17

What is Heronapyrrole B?

Biological Activity

Heronapyrrole B is a farnesylated 2-nitropyrrole bacterial metabolite that has been found in Streptomyces and has antibacterial activity.1,2 It is active against the Gram-positive bacteria S. aureus and B. subtilis (MICs = 1.8 and 7.5 μM, respectively) but not Gram-negative P. aeruginosa or E. coli.1

References

1.Raju, R., Piggott, A.M., Diaz, L.X.B., et al.Heronapyrroles A-C: farnesylated 2-nitropyrroles from an Australian marine-derived Streptomyces spOrg. Lett.12(22)5158-5161(2010) 2.Matsuo, T., Hashimoto, S., Nishikawa, K., et al.Total synthesis and complete stereochemical assignment of heronapyrroles A and BTetrahedron Letters565345-5348(2015)

Properties of Heronapyrrole B

Boiling point:	623.2±55.0 °C(Predicted)
Density	1.235±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: soluble
form	A solid
pka	13.84±0.50(Predicted)

Safety information for Heronapyrrole B

Computed Descriptors for Heronapyrrole B

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